El metabolismo del triptófano en la encrucijada de la inmunidad, la función de barrera y el microbioma en la dermatitis atópica

integrate findings from preclinical and clinical studies to describe disease-associated alterations in TRP metabolism in AD and their potential relevance to disease activity. In addition, we examine both existing and emerging therapeutic strategies aimed at correcting TRP metabolic imbalance, including pharmacological agents, dietary interventions, and probiotic supplementation. Overall, elucidating the multifaceted role of TRP metabolism in AD pathophysiology provides a rational foundation for developing more precise © 2026. The Author(s), under exclusive licence to Springer Science+Business