Insuficiencia hepática aguda en un adolescente tras el uso del agonista sintético REV-ERB SR9009

investigation excluded viral, autoimmune, metabolic and obstructive causes. Liver biopsy demonstrated severe hepatocellular injury with confluent and multiacinar necrosis, consistent with severe DILI. Following transplantation, liver biochemistry and synthetic function improved rapidly. This case highlights the hepatotoxic potential of unregulated supplements, the importance of obtaining a detailed exposure history in young patients with acute liver injury and the need for early recognition of progressive liver failure requiring timely Copyright © 2026 Saad Shams Bin Shaheen et al. Case Reports in Hepatology