De "Cuanto más, mejor" a "Equilibrio preciso": la curva en forma de U de la suplementación con vitamina D y la reevaluación de los niveles óptimos

considerations at the upper end of the U-shaped curve, and disease-specific metabolic alterations into a single, actionable clinical algorithm. This conceptual shift from indiscriminate supplementation to precision intervention offers a practical resolution to the ongoing clinical debate. Future research should prioritize the design of trials with deficient populations, ensuring adequate follow-up and systematic safety monitoring. The transition from universal supplementation to precision intervention signifies a shift in modern medicine's approach, moving from addressing deficiencies to managing complex