Resumen del estudio (idioma original)
turnover markers (both formation and resorption). Low urinary calcium excretion supported the presence of a skeletal mineral sink. This case highlights an HBS-like state after denosumab-induced osteoclast inhibition in high-turnover osteolytic lesions of MM. Renal impairment and extensive skeletal involvement were predisposing factors. Persistence of elevated resorption marker suggests incomplete suppression of bone resorption due to secondary hyperparathyroidism and renal impairment. Close monitoring and anticipatory mineral supplementation © The Author(s) 2026. Published by Oxford University Press on behalf of the
Traducción al español (IA · NME)
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Detalles bibliográficos
- Autores: Vaghasia N, Dutta A, Rupwane K, Farooqui K, Mithal A
- Publicado en: JCEM case reports
- PMID: 42170515
- DOI: 10.1210/jcemcr/luag137
