Perspectivas morfológicas y bioquímicas sobre los efectos renoprotectores del tratamiento combinado con N-acetilcisteína y glicina en la nefropatía diabética experimental

benefit than late subgroups. The combined NAC + GLY therapy (Group 5) demonstrated the strongest renoprotective effect, preserving renal structure and biochemical parameters closest to healthy controls. To conclude, early combined administration of glycine and N-acetylcysteine yields superior protection against diabetes-induced renal injury compared with individual treatments. These findings support the therapeutic potential of antioxidant-amino acid © 2026 The Author(s). Pharmacology Research & Perspectives published by British Pharmacological Society and American Society for Pharmacology and Experimental