La N-acetilcisteína mitiga la glicación y agregación de proteínas inducidas por d-ribosa a través de múltiples mecanismos protectores

fluorescence, with maximal protection observed at 300 μM. NAC exhibits pronounced anti-glycation and anti-aggregation effects by limiting oxidative stress and glycation-mediated protein modification. These findings demonstrate that NAC effectively attenuates d-ribose-induced glycation and protein aggregation in vitro and provide mechanistic insights into its anti-glycation properties through multiple complementary biochemical mechanisms. Further studies are warranted to evaluate its biological relevance in more complex © 2026 International Union of Biochemistry and Molecular Biology.