El preacondicionamiento con N-acetil cisteína (NAC) mejora la eficacia de las células madre mesenquimales derivadas de médula ósea para la curación de heridas por quemaduras en la piel

improved re-epithelialization, increased hydroxyproline content, and promoted collagen deposition and tissue regeneration. Furthermore, NAC-preconditioned BMSCs enhanced antioxidant defenses and upregulated SDF-1, CXCR4, VEGF-A, and IGF-1 expression in wound tissues. Collectively, these findings demonstrate that NAC preconditioning enhances the survival, antioxidant capacity, paracrine activity, and regenerative potential of BMSCs, resulting in improved burn wound healing. NAC-preconditioned BMSCs may represent a promising strategy for stem Copyright © 2026 British Trauma Society. Published by Elsevier Ltd. All rights