Efectos nefroprotectores del tratamiento con N-acetilcisteína y montelukast post-contraste en un modelo de rata de lesión renal aguda inducida por contraste

animals receiving NAC, montelukast, or the combined regimen generally showed improved biochemical and histopathological findings. Glutathione (GSH) levels were highest, and mean histopathological injury scores were numerically lowest in the combination group; however, combined treatment did not consistently outperform monotherapy across the assessed outcomes. This protocol provides a controlled preclinical framework for evaluating post-contrast interventions in CI-AKI, and the findings warrant further experimental investigation of NAC and montelukast without establishing clinical efficacy or a combination-specific