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Complejo de Péptidos de Colágeno de Pescado Oral Mejora la Rejuvenecimiento de la Piel y Biomarcadores de Salud Sistémica: Un Estudio Observacional Prospectivo de 90 Días

Título original: Oral Fish Collagen Peptide Complex Enhances Skin Rejuvenation and Systemic Health Biomarkers: A 90 Day Prospective Observational Study

Journal of cosmetic dermatology · Huang J, Chen C, Zhang M, Li J, Wang R, Wang Y · 1 de abril de 2026

Resumen del estudio

OBJECTIVE: This study aims to evaluate the effects of Fish Collagen Peptide Nutritional Combination (FCPNC) on facial skin rejuvenation and biochemical indicators, including body mass index (BMI), blood lipids, superoxide dismutase (SOD), and bone mineral density in participants. METHODS: This study involved 29 female participants aged 20-55 years, who consumed FCPNC daily for 90 days. Facial skin changes, including wrinkle percentage, pigmentation area, skin hydration, and elasticity, were assessed before and after the intervention. Additionally, BMI, blood tests, and bone mineral density were measured on Day 0 and Day 90. Participants completed questionnaires on skin, nails, hair, and product satisfaction at Days 30, 60, and 90. RESULTS: After 30, 60, and 90 days, participants exhibited significant improvements in skin hydration, elasticity, and a reduction in wrinkle area percentage. This nutritional combination not only improved skin health but also yielded systemic benefits, including normalizing BMI in 58.33% of overweight participants. SOD activity increased by 31.03%, reflecting enhanced antioxidant capacity. Additionally, calcium levels rose by 48.28%, suggesting potential bone health benefits. Satisfaction surveys revealed increasing positive feedback, with 93% of participants rating the product favorably by the study's conclusion (score ≥ 4). CONCLUSIONS: These findings suggest that FCPNC may positively influence skin health and overall health status, emphasizing its potential as a functional food. However, further large-scale randomized controlled trials are necessary to validate these results. © 2026 The Author(s). Journal of Cosmetic Dermatology published by Wiley Periodicals LLC. DOI: 10.1111/jocd.70841 PMCID: PMC13062880

Detalles bibliográficos

  • Autores: Huang J, Chen C, Zhang M, Li J, Wang R, Wang Y
  • Publicado en: Journal of cosmetic dermatology
  • Fecha: 2026 Apr
  • PMID: 41952536
  • DOI: 10.1111/jocd.70841

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Esta evidencia se ha indexado automáticamente desde la base de datos PubMed (NCBI/NLM, US National Institutes of Health). El resumen mostrado es propiedad intelectual de sus autores y editorial.

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