El extracto de hoja de Physalis angulata atenúa la neurotoxicidad inducida por H(2)O(2) en pez cebra a través de evidencia metabolómica de la restauración de la vía antioxidante

zebrafish embryo homogenates provided direct in vivo biochemical evidence of antioxidant pathway modulation, demonstrating that PA extract mitigated metabolic disruption by restoring amino acid metabolism (glycine, serine, and threonine), glutathione synthesis, glycerophospholipid homeostasis, and one-carbon pool metabolism. These findings demonstrate that P. angulata exerts multi-target neuroprotection by restoring antioxidant pathways and promoting metabolic homeostasis, supporting its potential as a natural therapeutic candidate for oxidative stress-related neurological conditions.