Efectos potenciales de apoyo de los péptidos de colágeno AP en la hidratación de la piel en un modelo murino de dermatitis atópica inducida por oxazolone

significantly increased skin hydration, accompanied by restoration of filaggrin expression and significantly reduced expression of TSLP, p-STAT3, and p-ERK. In contrast, mast cell infiltration, CD3+ and CD4+ T cell infiltration, and the expression of inflammatory cytokines, including IFN-γ, IL-4, IL-13, and IL-31, showed a tendency toward reduction but did not reach statistical significance. These findings suggest that APCP may not exert broad immunosuppressive effects, but may contribute to the alleviation of AD symptoms through improvements in skin hydration, supporting its potential as an adjunctive agent for AD.