Imagen de superresolución con una sonda fluorescente dirigida a mitocondrias: Evaluación de la lesión hepatorrenal inducida por quimioterapia

further validate the tissue-damage mechanisms of these two drugs and evaluate the protective effect of N-acetylcysteine (NAC) on the kidney and of silybin on the liver against drug-induced injury. The results demonstrate that both protective agents effectively alleviate hepatokidney damage without compromising the anti-tumor efficacy of the chemotherapeutic drugs. Hence, this work elucidates the anti-tumor and tissue injury mechanisms of DDP and SU in complex biological systems, providing a new strategy for mitigating drug-induced organ toxicity and offering a solid experimental basis for the rational design of