Inducción sinérgica de la muerte celular inmunogénica en células de cáncer de mama triple negativo por plasma frío atmosférico y campo eléctrico pulsado

cytotoxicity of CAP was completely reversed by Catalase and N-Acetylcysteine (NAC), while that of PEF was only reversed by NAC. Furthermore, CAP before PEF treatment had the strongest killing and pro-apoptotic effects on TNBC cells, and the increase in ICD markers was the most significant. Mechanically, pre-treatment with CAP allowing PEF to cause more extensive membrane disintegration. CAP before PEF treatment also triggered the most intense mitochondrial oxidative stress, leading to a significant rise in intracellular Copyright © 2026 The Authors. Published by Elsevier B.V. All rights reserved.