La vitamina D₃ en la prevención y terapia del cáncer: mecanismos moleculares, evidencia clínica y perspectivas futuras

promising therapeutic benefits as an adjunct to conventional cancer treatment, particularly in patients with vitamin D deficiency, although findings remain inconsistent across cancer types and clinical settings. Overall, current evidence supports vitamin D₃ as a safe, cost-effective, and promising adjuvant strategy in oncology; however, its routine clinical application requires validation through well-designed, large-scale randomized controlled trials to establish optimal dosing strategies, identify responsive patient populations, © 2026. The Author(s), under exclusive licence to Springer Nature B.V.