Secondary analysis of omega-3 supplementation: Alteration of lipid mediators and inflammation in older adults engaged in a home-based and vibration exercise program

Resumen del estudio

= .003) declined similarly in both groups. Supplementation was associated with greater reductions in interleukin 10 and interleukin 1 receptor antagonist, and a larger increase in insulin-like growth factor 1. Changes in PGE2 correlated with C reactive protein (ρ = -0.412, P = .008) and like growth factor 1 (ρ = 0.345, P = .029). Omega-3 supplementation selectively lowered PGE2 independent of exercise effects, while exercise contributed to decreases in LTB4 and RvE1. These findings indicate that omega-3 supplementation modifies lipid mediators Copyright © 2026 The Authors. Published by Elsevier Inc. All rights reserved.